You can edit hotkeys by opening up Exilebuddy > Settings > Global > GlobalSettings.json. Use this site to cipher your keys: https://msdn.microsoft.com/en-us/library/aa243025(v=vs.60).aspx Example: Changing the default pause button (which is technically just stop / start, not a true pause) ... you would change. Code: "StartStopBotKey": 112, "StartStopBotMod": 0, 112 = F1 0 = No modifiers (aka, no shift, alt, control, etc) So the above change allows you to use F1 to start and stop the bot.
There's no "pause" hotkey in the sense of letting the bot run but not do anything by design. EB has to hook input and interacts pretty heavily with the client to work, so you need to Stop the bot to do things and then start it up again.